EXTL1 Antibody (PACO19637)
- SKU:
- PACO19637
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Frequently bought together:
Description
| Antibody Name: | EXTL1 Antibody (PACO19637) |
| Antibody SKU: | PACO19637 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:1000-1:2000, IHC:1:25-1:100 |
| Species Reactivity: | Human, Mouse |
| Immunogen: | Synthetic peptide of human EXTL1 |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | The image on the left is immunohistochemistry of paraffin-embedded Human prostate cancer tissue using PACO19637(EXTL1 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200). |
 | The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using PACO19637(EXTL1 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200). |
| Background: | This gene is a member of the multiple exostoses (EXT) family of glycosyltransferases, which function in the chain polymerization of heparan sulfate and heparin. The encoded protein harbors α 1,4- N-acetylglucosaminyltransferase activity, and is involved in chain elongation of heparan sulfate and possibly heparin. |
| Synonyms: | exostosin-like glycosyltransferase 1 |
| UniProt Protein Function: | EXTL1: Probable glycosyltransferase. Belongs to the glycosyltransferase 47 family.Protein type: Membrane protein, integral; Transferase; Glycan Metabolism - heparan sulfate biosynthesis; EC 2.4.1.224Chromosomal Location of Human Ortholog: 1p36.1Biological Process: skeletal development |
| UniProt Protein Details: | |
| NCBI Summary: | This gene is a member of the multiple exostoses (EXT) family of glycosyltransferases, which function in the chain polymerization of heparan sulfate and heparin. The encoded protein harbors alpha 1,4- N-acetylglucosaminyltransferase activity, and is involved in chain elongation of heparan sulfate and possibly heparin. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q92935 |
| NCBI GenInfo Identifier: | 93141259 |
| NCBI Gene ID: | 2134 |
| NCBI Accession: | Q92935.2 |
| UniProt Secondary Accession: | Q92935,Q6GSC1 |
| UniProt Related Accession: | Q92935 |
| Molecular Weight: | 74,697 Da |
| NCBI Full Name: | Exostosin-like 1 |
| NCBI Synonym Full Names: | exostosin like glycosyltransferase 1 |
| NCBI Official Symbol: | EXTL1Â Â |
| NCBI Official Synonym Symbols: | EXTLÂ Â |
| NCBI Protein Information: | exostosin-like 1 |
| UniProt Protein Name: | Exostosin-like 1 |
| UniProt Synonym Protein Names: | Exostosin-L; Glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase; Multiple exostosis-like protein |
| Protein Family: | Exostosin |
| UniProt Gene Name: | EXTL1Â Â |
| UniProt Entry Name: | EXTL1_HUMAN |
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