The Exportin-6 Polyclonal Antibody (CAB10401) is a valuable tool for researchers studying the protein Exportin-6, which plays a key role in the nucleocytoplasmic transport of proteins. This polyclonal antibody, generated in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications.By specifically binding to Exportin-6, this antibody enables accurate detection and analysis of the protein in various cell types. This makes it an essential tool for researchers in fields such as cell biology, molecular biology, and biochemistry who are investigating the mechanisms of protein transport and cellular communication.
Exportin-6 is known for its involvement in the transport of cargo proteins from the nucleus to the cytoplasm, a process essential for various cellular functions. Understanding the role of Exportin-6 can provide insights into gene expression regulation, cell cycle progression, and signal transduction pathways. By using the Exportin-6 Polyclonal Antibody in their experiments, researchers can advance their understanding of these fundamental cellular processes and contribute to the development of new therapeutic strategies targeting nucleocytoplasmic transport mechanisms.
Product Name:
XPO6 Rabbit Polyclonal Antibody
SKU:
CAB10401
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 290-530 of human XPO6 (NP_055986.1).
The protein encoded by this gene is a member of the importin-beta family. Members of this family are regulated by the GTPase Ran to mediate transport of cargo across the nuclear envelope. This protein has been shown to mediate nuclear export of profilin-actin complexes. A pseudogene of this gene is located on the long arm of chromosome 14. Alternative splicing results in multiple transcript variants that encode different protein isoforms.
Purification Method:
Affinity purification
Gene ID:
23214
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates, using XPO6 Rabbit pAb (CAB10401) at 1:2000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
