The Exportin-5 Rabbit Monoclonal Antibody (CAB3813) is a cutting-edge tool for researchers studying Exportin-5, a key protein involved in nucleocytoplasmic transport. This antibody, developed using rabbit monoclonal technology, exhibits high specificity and sensitivity towards Exportin-5 in various experimental settings. Validated for use in applications such as immunofluorescence and immunoprecipitation, it offers robust performance for detecting and studying Exportin-5 dynamics in cells.Exportin-5 plays a crucial role in the transport of RNA molecules from the nucleus to the cytoplasm, making it a central player in gene expression regulation.
Dysregulation of Exportin-5 function has been associated with diseases such as cancer and developmental disorders, highlighting the importance of understanding its mechanisms of action. By targeting Exportin-5 with this monoclonal antibody, researchers can gain valuable insights into its function and potential therapeutic applications in various pathophysiological conditions.
Product Name:
Exportin 5 (XPO5) Rabbit Monoclonal Antibody
SKU:
CAB3813
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human Exportin 5 (XPO5) (Q9HAV4).
This gene encodes a member of the karyopherin family that is required for the transport of small RNAs and double-stranded RNA-binding proteins from the nucleus to the cytoplasm. The encoded protein translocates cargo through the nuclear pore complex in a RanGTP-dependent process.
Purification Method:
Affinity purification
Gene ID:
57510
Clone Number:
ARC0838
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using Exportin 5 (XPO5) (XPO5) Rabbit mAb (CAB3813) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
