The Exportin-5 Polyclonal Antibody (CAB6790) is a vital tool for researchers studying the role of Exportin-5 in nucleocytoplasmic transport and RNA export processes. This antibody, generated in rabbits, exhibits high specificity and sensitivity towards human Exportin-5 protein, allowing for accurate detection and analysis in various cell types.Exportin-5 is a key mediator of protein trafficking, exporting pre-microRNAs from the nucleus to the cytoplasm for further processing. Dysregulation of Exportin-5 has been implicated in various diseases, including cancer and neurological disorders.
By using the Exportin-5 Polyclonal Antibody, researchers can investigate the mechanisms underlying Exportin-5 function and its potential therapeutic implications.Whether studying RNA export mechanisms, investigating disease pathways, or developing targeted therapies, the Exportin-5 Polyclonal Antibody is a valuable asset for researchers in the fields of molecular biology, cell biology, and drug discovery. Its reliability and specificity make it an essential tool for advancing our understanding of Exportin-5 biology and its role in human health and disease.
Product Name:
Exportin 5 (XPO5) Rabbit Polyclonal Antibody
SKU:
CAB6790
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 925-1204 of human Exportin 5 (Exportin 5 (XPO5)) (NP_065801.1).
WB,1:2000 - 1:10000 IF/ICC,1:100 - 1:500 IP,0.5μg-4μg antibody for 200μg-400μg extracts of whole cells
Synonyms:
exp5; Exportin 5 (XPO5)
Positive Sample:
K-562
Conjugate:
Unconjugated
Cellular Localization:
Cytoplasm, Nucleus.
Calculated MW:
136kDa
Observed MW:
136kDa
This gene encodes a member of the karyopherin family that is required for the transport of small RNAs and double-stranded RNA-binding proteins from the nucleus to the cytoplasm. The encoded protein translocates cargo through the nuclear pore complex in a RanGTP-dependent process.
Purification Method:
Affinity purification
Gene ID:
57510
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates, using Exportin 5 (XPO5) Rabbit pAb (CAB6790) at 1:10000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
