The ExoSC8 Polyclonal Antibody (CAB4507) is a powerful tool for researchers studying ExoSC8, a key protein involved in exosome secretion and cellular communication. This antibody, produced through the immunization of rabbits, exhibits high specificity and sensitivity in detecting ExoSC8 in human samples, making it ideal for Western blot applications. By targeting the ExoSC8 protein, researchers can gain valuable insights into exosome biogenesis and its role in intercellular signaling pathways.Exosomes are small vesicles released by cells that play a critical role in cell-to-cell communication and the transfer of biomolecules. ExoSC8, as a component of the exosome secretion machinery, is essential for the proper formation and release of exosomes.
By studying ExoSC8 with this antibody, researchers can further understand the mechanisms underlying exosome biogenesis and its implications in various physiological and pathological processes.The ExoSC8 Polyclonal Antibody is a valuable tool for investigating the complex world of exosome biology and its implications in cancer, neurodegenerative diseases, and other pathological conditions. By utilizing this antibody in research studies, scientists can uncover novel insights into the roles of exosomes in health and disease, ultimately paving the way for the development of innovative therapeutic strategies targeting exosome-mediated communication.
Product Name:
EXOSC8 Rabbit Polyclonal Antibody
SKU:
CAB4507
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-276 of human EXOSC8 (NP_852480.1).
This gene encodes a 3'-5' exoribonuclease that specifically interacts with mRNAs containing AU-rich elements. The encoded protein is part of the exosome complex that is important for the degradation of numerous RNA species. A pseudogene of this gene is found on chromosome 6.
Purification Method:
Affinity purification
Gene ID:
11340
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using EXOSC8 antibody (CAB4507) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
