The Exosc5 Polyclonal Antibody (CAB15870) is specifically designed for research involving Exosc5, a crucial component of the exosome complex responsible for RNA degradation. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for Western blot applications. By binding to the Exosc5 protein, researchers can accurately detect and analyze its expression in a variety of cell types, making it an ideal tool for studies in RNA biology and gene regulation.Exosc5 is known for its role in RNA processing and degradation, making it essential for maintaining RNA quality control and gene expression regulation.
Understanding the function of Exosc5 is integral to unraveling the mechanisms of RNA metabolism and identifying potential therapeutic targets for diseases linked to RNA dysregulation. Researchers studying gene expression, RNA degradation pathways, and RNA-related disorders will benefit from the precision and reliability of the Exosc5 Polyclonal Antibody in their experimental investigations.
Product Name:
EXOSC5 Rabbit Polyclonal Antibody
SKU:
CAB15870
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-235 of human EXOSC5 (NP_064543.3).
Predicted to enable RNA binding activity. Involved in DNA deamination and exonucleolytic catabolism of deadenylated mRNA. Acts upstream of or within defense response to virus. Located in nucleolus; nucleoplasm; and transcriptionally active chromatin. Part of exosome (RNase complex).
Purification Method:
Affinity purification
Gene ID:
56915
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from rat pancreas, using EXOSC5 Rabbit pAb (CAB15870) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
