The EXOSC4 Polyclonal Antibody (CAB9147) is a valuable tool for researchers studying the exosome component 4 (EXOSC4) protein, which is a key player in RNA processing and degradation. This antibody, generated in rabbits, is highly reactive with human samples and suitable for use in Western blotting applications. By specifically binding to the EXOSC4 protein, researchers can easily detect and analyze its expression in various cell types.EXOSC4 is part of the exosome complex, which is involved in RNA degradation and processing, making it essential for maintaining cellular homeostasis.
Dysregulation of exosome components like EXOSC4 has been linked to various diseases, including cancer and neurodegenerative disorders. By studying the role of EXOSC4, researchers can gain valuable insights into disease mechanisms and potentially identify new therapeutic targets.Overall, the EXOSC4 Polyclonal Antibody (CAB9147) is a reliable tool for investigating the function of EXOSC4 in different biological processes, making it a valuable asset for research in molecular biology, cancer biology, and neuroscience.
Product Name:
EXOSC4 Rabbit Polyclonal Antibody
SKU:
CAB9147
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-245 of human EXOSC4 (NP_061910.1).
Enables mRNA 3'-UTR AU-rich region binding activity. Involved in nucleic acid metabolic process and positive regulation of cell growth. Acts upstream of or within defense response to virus. Located in cytosol; nucleoplasm; and transcriptionally active chromatin. Part of exosome (RNase complex).
Purification Method:
Affinity purification
Gene ID:
54512
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using EXOSC4 Rabbit pAb (CAB9147) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
