The Exosc2 Polyclonal Antibody (CAB10450) is a valuable tool for researchers studying Exosc2, a crucial component of the RNA exosome complex involved in RNA processing and degradation. This antibody, generated in rabbits, exhibits high reactivity with human samples and has been validated for use in various applications including Western blotting. By specifically recognizing the Exosc2 protein, this antibody enables detailed analysis and detection of Exosc2 expression in different cell types.Exosc2, also known as RRP4, plays a vital role in maintaining RNA quality control and regulating gene expression. Dysregulation of Exosc2 has been linked to various diseases including cancer, neurodegenerative disorders, and developmental abnormalities.
Investigating the function and expression of Exosc2 is therefore crucial for understanding its implications in these pathological conditions and identifying potential therapeutic targets.Overall, the Exosc2 Polyclonal Antibody is a reliable tool for researchers interested in unraveling the complex roles of Exosc2 in RNA metabolism and its impact on disease development. Its high specificity and sensitivity make it an ideal choice for studies in molecular biology, cancer research, and other related fields.
Product Name:
EXOSC2 Rabbit Polyclonal Antibody
SKU:
CAB10450
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-293 of human EXOSC2 (NP_055100.2).
Predicted to enable RNA binding activity. Involved in positive regulation of cell growth. Located in cytoplasm; nucleolus; and nucleoplasm. Part of nuclear exosome (RNase complex).
Purification Method:
Affinity purification
Gene ID:
23404
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using EXOSC2 Rabbit pAb (CAB10450) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
