The ExoSC10 Rabbit Polyclonal Antibody (CAB17519) is a valuable tool for research involving ExoSC10, a protein involved in exosome biogenesis and secretion. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for Western blot applications. By binding to the ExoSC10 protein, researchers can effectively detect and analyze this critical molecule in a variety of cell types.ExoSC10 is essential for the proper formation and release of exosomes, extracellular vesicles that play important roles in intercellular communication and signaling. Dysregulation of exosome production has been implicated in various diseases, including cancer, neurodegenerative disorders, and infectious diseases.
Therefore, studying the function of ExoSC10 is key to understanding the mechanisms underlying these pathologies and developing potential therapeutic interventions.By using the ExoSC10 Rabbit Polyclonal Antibody, researchers can gain valuable insights into the biology of exosomes and their role in disease progression. This antibody is a valuable tool for investigations in cell biology, molecular biology, and biomedicine, providing a deeper understanding of exosome biology and its implications for human health.
Product Name:
EXOSC10 Rabbit Polyclonal Antibody
SKU:
CAB17519
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 586-885 of human EXOSC10 (NP_001001998.1).
Enables 3'-5'-exoribonuclease activity. Involved in several processes, including RNA catabolic process; maturation of 5.8S rRNA; and negative regulation of telomere maintenance via telomerase. Located in cytosol; nuclear lumen; and transcriptionally active chromatin. Part of nuclear exosome (RNase complex).
Purification Method:
Affinity purification
Gene ID:
5394
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using EXOSC10 Rabbit pAb (CAB17519) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
