The Exonuclease 1 Polyclonal Antibody (CAB1941) is a valuable tool for research involving Exonuclease 1, an essential enzyme involved in DNA repair and maintenance. This antibody, produced in rabbits, is highly specific for human samples and has been validated for use in Western blot and immunohistochemistry applications. By targeting the Exonuclease 1 protein, this antibody enables researchers to detect and analyze the enzyme in various cell types, making it ideal for studies in genetics, cancer research, and molecular biology.Exonuclease 1 is crucial for maintaining genomic stability by repairing DNA damage and promoting accurate DNA replication.
Dysregulation of this enzyme has been linked to various diseases, including cancer and genetic disorders. By studying the function of Exonuclease 1, researchers can gain insight into the mechanisms of DNA repair and potential therapeutic targets for diseases associated with genomic instability. This antibody provides a valuable tool for advancing our understanding of Exonuclease 1 and its role in cellular processes.
Product Name:
EXO1 Rabbit Polyclonal Antibody
SKU:
CAB1941
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 601-846 of human EXO1 (NP_006018.4).
This gene encodes a protein with 5' to 3' exonuclease activity as well as an RNase H activity. It is similar to the Saccharomyces cerevisiae protein Exo1 which interacts with Msh2 and which is involved in mismatch repair and recombination. Alternative splicing of this gene results in three transcript variants encoding two different isoforms.
Purification Method:
Affinity purification
Gene ID:
9156
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using EXO1 Rabbit pAb (CAB1941) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
