The ExoC6 Antibody (PACO09165) is a crucial tool for researchers studying exosome biology, specifically targeting the exosome component ExoC6. This polyclonal antibody, produced in rabbits, shows high reactivity with human samples and has been validated for use in various applications, including Western blotting.Exosomes are nano-sized vesicles secreted by cells that play a role in intercellular communication, including in immune responses, cancer progression, and other physiological processes.
The ExoC6 protein, a key player in exosome formation and function, is a promising target for studying these processes.By using the ExoC6 Antibody, researchers can effectively detect and analyze ExoC6 protein levels in different cell types, aiding in the understanding of exosome biology and its implications in various diseases. This antibody is particularly useful for studies in cancer research, immunology, and other fields where exosome-mediated processes are of interest.
EXOC6: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. Together with RAB11A, RAB3IP, RAB8A, PARD3, PRKCI, ANXA2, CDC42 and DNMBP promotes transcytosis of PODXL to the apical membrane initiation sites (AMIS), apical surface formation and lumenogenesis. Belongs to the SEC15 family.Chromosomal Location of Human Ortholog: 10q23.33Cellular Component: plasma membrane; exocyst; cytosolBiological Process: protein transport; cellular protein metabolic process; organelle organization and biogenesis; erythrocyte differentiation; vesicle docking during exocytosis
UniProt Protein Details:
NCBI Summary:
The product of this gene belongs to the SEC15 family. It is highly similar to the protein encoded by Saccharomyces cerevisiae SEC15 gene. This protein is essential for vesicular traffic from the Golgi apparatus to the cell surface in yeast. It is one of the components of a multiprotein complex required for exocytosis. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
