The ExoC5 Polyclonal Antibody (CAB9282) is a valuable tool for researchers studying ExoC5, a protein involved in exosome secretion and intercellular communication. This antibody, generated in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to the ExoC5 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it an ideal choice for studies in the fields of exosome biology, cell signaling, and cancer research.
ExoC5 plays a crucial role in regulating exosome release and cargo sorting, making it a key player in cellular communication processes. Understanding the function of ExoC5 is essential for uncovering its potential implications in diseases such as cancer, neurodegenerative disorders, and immune-related conditions. By targeting ExoC5 with this polyclonal antibody, researchers can gain valuable insights into its role in exosome-mediated cell-to-cell communication and its potential as a therapeutic target in various pathological contexts.
Product Name:
EXOC5 Rabbit Polyclonal Antibody
SKU:
CAB9282
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 340-610 of human EXOC5 (NP_006535.1).
The protein encoded by this gene is a component of the exocyst complex, a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and functions of exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. The complex is also essential for the biogenesis of epithelial cell surface polarity.
Purification Method:
Affinity purification
Gene ID:
10640
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using EXOC5 antibody (CAB9282) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
