EXOC4 Rabbit Polyclonal Antibody (CAB12374)
- SKU:
- CAB12374
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | EXOC4 Rabbit Polyclonal Antibody |
SKU: | CAB12374 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human EXOC4 (NP_068579.3). |
Sequence: | MAAE AAGG KYRS TVSK SKDP SGLL ISVI RTLS TSDD VEDR ENEK GRLE EAYE KCDR DLDE LIVQ HYTE LTTA IRTY QSIT ERIT NSRN KIKQ VKEN LLSC KMLL HCKR DELR KLWI EGIE HKHV LNLL DEIE NIKQ VPQK LEQC MASK HYLS ATDM LVSA VESL EGPL LQVE GLSD LRLE LHSK KMNL HLVL IDEL HRHL YIKS TSRV VQRN KEKG KISS LVKD ASVP LIDV TNLP TPRK FLDT SHYS TAGS SSVR EINL QDIK EDLE LDPE ENST LFMG |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | SEC8; Sec8p; SEC8L1; EXOC4 |
Positive Sample: | A-431,Jurkat,Mouse brain,Mouse thymus,Mouse liver,Rat brain |
Conjugate: | Unconjugated |
Cellular Localization: | centrosome, cytoplasm, cytosol, exocyst, growth cone membrane, myelin sheath abaxonal region, plasma membrane, synapse |
Calculated MW: | 110kDa |
Observed MW: | 122kDa |
The protein encoded by this gene is a component of the exocyst complex, a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and functions of exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. The complex is also essential for the biogenesis of epithelial cell surface polarity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Purification Method: | Affinity purification |
Gene ID: | 60412 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |