The EXOC4 Polyclonal Antibody (CAB12374) is a valuable tool for researchers studying the exocyst complex component 4 (EXOC4), a key regulator of intracellular vesicle trafficking. This antibody, raised in rabbits, demonstrates high specificity and sensitivity for detection of EXOC4 in human samples, making it ideal for use in Western blot applications.EXOC4 is essential for proper vesicle transport and secretion, playing a crucial role in diverse cellular processes such as cell growth, division, and signaling. Dysregulation of EXOC4 has been implicated in various diseases, including cancer and neurological disorders, highlighting the importance of studying its function.
By using the EXOC4 Polyclonal Antibody, researchers can gain valuable insights into the role of EXOC4 in cellular processes and disease pathogenesis. Its high reactivity and specificity make it a reliable tool for investigating the function of EXOC4 in different cell types and disease models, providing valuable information for drug development and therapeutic strategies targeting vesicle trafficking pathways.
Product Name:
EXOC4 Rabbit Polyclonal Antibody
SKU:
CAB12374
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human EXOC4 (NP_068579.3).
The protein encoded by this gene is a component of the exocyst complex, a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and functions of exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. The complex is also essential for the biogenesis of epithelial cell surface polarity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Purification Method:
Affinity purification
Gene ID:
60412
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using EXOC4 Rabbit pAb (CAB12374) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
