The EXOC3 Polyclonal Antibody (CAB17635) is a valuable tool for researchers studying EXOC3, a key protein involved in membrane trafficking and vesicle exocytosis. This rabbit-derived antibody is highly specific and sensitive, making it ideal for experiments requiring precise detection of EXOC3 in various sample types.EXOC3 plays a crucial role in the regulation of vesicle transport and secretion processes within cells, making it an important target for investigation in cell biology and neurobiology research. The antibody is validated for use in Western blotting and immunofluorescence applications, providing researchers with reliable results and clear visualization of EXOC3 expression in experimental settings.
By using the EXOC3 Polyclonal Antibody, researchers can gain insights into the function and regulation of EXOC3, which has implications for understanding cellular communication, neurotransmitter release, and other biological processes. This antibody offers researchers a powerful tool for exploring the role of EXOC3 in health and disease, paving the way for new discoveries and potential therapeutic targets in the field of molecular biology.
Product Name:
EXOC3 Rabbit Polyclonal Antibody
SKU:
CAB17635
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 396-745 of human EXOC3 (NP_009208.2).
cytosol, exocyst, Golgi apparatus, growth cone, perinuclear region of cytoplasm, presynaptic membrane
Calculated MW:
86kDa
Observed MW:
87kDa
The protein encoded by this gene is a component of the exocyst complex, a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and functions of exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. The complex is also essential for the biogenesis of epithelial cell surface polarity.
Purification Method:
Affinity purification
Gene ID:
11336
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using EXOC3 Rabbit pAb (CAB17635) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5min.
