EXOC3 Rabbit Polyclonal Antibody (CAB17635)
- SKU:
- CAB17635
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | EXOC3 Rabbit Polyclonal Antibody |
SKU: | CAB17635 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 396-745 of human EXOC3 (NP_009208.2). |
Sequence: | RKAL ETDK KDWV KETE PEAD QDGY YQTT LPAI VFQM FEQN LQVA AQIS EDLK TKVL VLCL QQMN SFLS RYKD EAQL YKEE HLRN RQHP HCYV QYMI AIIN NCQT FKES IVSL KRKY LKNE VEEG VSPS QPSM DGIL DAIA KEGC SGLL EEVF LDLE QHLN ELMT KKWL LGSN AVDI ICVT VEDY FNDF AKIK KPYK KRMT AEAH RRVV VEYL RAVM QKRI SFRS PEER KEGA EKMV REAE QLRF LFRK LASG FGED VDGY CDTI VAVA EVIK LTDP SLLY LEVS TLVS KYPD IRDD HIGA LLAV RGDA SRDM KQTI METL EQGP AQAS PSYV PLFK DIVV PSLN VAKL LK |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | SEC6; Sec6p; SEC6L1; EXOC3 |
Positive Sample: | PC-3,U-251MG,Mouse brain,Mouse lung,Rat brain |
Conjugate: | Unconjugated |
Cellular Localization: | cytosol, exocyst, Golgi apparatus, growth cone, perinuclear region of cytoplasm, presynaptic membrane |
Calculated MW: | 86kDa |
Observed MW: | 87kDa |
The protein encoded by this gene is a component of the exocyst complex, a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and functions of exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. The complex is also essential for the biogenesis of epithelial cell surface polarity.
Purification Method: | Affinity purification |
Gene ID: | 11336 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |