null

EXOC2 Monoclonal Antibody

SKU:
CAB23562
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Applications:
WB
$167 - $635
Frequently bought together:

Description

EXOC2 Monoclonal Antibody (CAB23562)

The EXOC2 Monoclonal Antibody is a powerful tool for researchers studying the EXOC2 protein, a key component of the exocyst complex involved in vesicle trafficking and secretion processes. This antibody, produced through hybridoma technology, specifically targets EXOC2 in human samples and is validated for use in various applications such as immunofluorescence and immunohistochemistry.EXOC2 plays a crucial role in regulating vesicle docking and fusion at the plasma membrane, making it essential for cellular secretion processes in various cell types. Dysregulation of EXOC2 has been linked to disorders such as cancer, neurodegenerative diseases, and diabetes, highlighting its importance in cellular function and disease pathology.

By utilizing the EXOC2 Monoclonal Antibody, researchers can accurately detect and study the expression and localization of EXOC2 in different cellular contexts, providing valuable insights into vesicle trafficking mechanisms and potential therapeutic targets for various diseases. Whether investigating basic cellular processes or disease mechanisms, this antibody is a reliable tool for advancing research in cell biology and molecular pathology.

Product Name:EXOC2 Monoclonal Antibody
Product Code:CAB23562
Reactivity:Human, Mouse, Rat
Applications:Western blotting
Host Species:Rabbit
Purification Method:Affinity purification
Isotype:IgG
Clone No:ARC3126
Reactivity:Human, Mouse, Rat
Tested Applications:WB, ELISA
Key Applications:Western blotting
Recommended Dilution:WB 1:200-1:500
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3.
Positive Samples:K-562, BxPC-3, SH-SY5Y, Mouse brain, Rat brain

The protein encoded by this gene is a component of the exocyst complex, a multi-protein complex essential for the polarized targeting of exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and the functions of the exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. This interaction has been shown to mediate filopodia formation in fibroblasts. This protein has been shown to interact with the Ral subfamily of GTPases and thereby mediate exocytosis by tethering vesicles to the plasma membrane. Alternative splicing results in multiple transcript variants.

Immunogen:Recombinant protein of human EXOC2.
Sequence:Email for sequence
Synonyms:SEC5, Sec5p, SEC5L1, NEDFACH
Calculated MW:104kDa
Observed MW:100kDa

Related Products