The EVL Antibody (PAC09160) is a high-quality polyclonal antibody designed for use in research studies involving EVL, a key protein involved in cell migration and cytoskeleton organization. This antibody, produced in rabbits, shows strong reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to the EVL protein, this antibody allows for precise detection and analysis of EVL in various cell types, making it an excellent tool for researchers in the fields of cell biology and cancer research.
EVL, also known as Ena/VASP-like protein, plays a crucial role in regulating actin dynamics and cell morphology, which are essential processes for cell movement and shape changes. Its involvement in these cellular functions makes EVL a target of interest for studying processes like cell migration, invasion, and metastasis in cancer research. By understanding the mechanisms by which EVL functions, researchers can gain valuable insights into potential therapeutic strategies for cancer treatment and other diseases involving aberrant cell motility.
EVL: Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance and lamellipodial and filopodial dynamics in migrating cells. EVL enhances actin nucleation and polymerization. Required to transform actin polymerization into active movement for the propulsive force of Listeria monocytogenes. Belongs to the Ena/VASP family. 2 isoforms of the human protein are produced by alternative splicing.Protein type: Motility/polarity/chemotaxis; CytoskeletalChromosomal Location of Human Ortholog: 14q32.2Cellular Component: cytoplasm; cytosol; focal adhesion; lamellipodium; membraneMolecular Function: profilin binding; protein binding; SH3 domain bindingBiological Process: actin filament organization; actin polymerization and/or depolymerization; axon guidance; positive regulation of stress fiber formation
