The ETV7 Polyclonal Antibody (CAB6255) is a valuable tool for researchers studying ETV7, a transcription factor known to play a role in various biological processes, including cell growth and differentiation. This antibody, derived from rabbits, exhibits high reactivity with human samples and is specifically validated for use in Western blot applications. By targeting the ETV7 protein, this antibody allows for precise detection and analysis in a variety of cell types, making it an essential component for research in molecular biology and cancer studies.
ETV7, also called TEL-2, is a key player in gene regulation and has been implicated in several diseases, including leukemia and solid tumors. Its involvement in controlling cell proliferation and survival makes it a promising target for therapeutic interventions aimed at combating cancer and other related disorders. Understanding the function of ETV7 at the molecular level is essential for developing targeted therapies that can effectively modulate its activity in disease settings.
Product Name:
ETV7 Rabbit Polyclonal Antibody
SKU:
CAB6255
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-210 of human ETV7 (NP_057219.1).
The protein encoded by this gene belongs to the ETS family of transcription factors, which is a large group of evolutionarily conserved transcriptional regulators that play an important role in a variety of cellular processes throughout development and differentiation, and are involved in oncogenesis as well. This protein is predominantly expressed in hematopoietic tissues. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene (PMID:11108721).
Purification Method:
Affinity purification
Gene ID:
51513
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using ETV7 antibody (CAB6255) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
