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ETV6 Rabbit Polyclonal Antibody (CAB15668)

SKU:
CAB15668
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Epigenetics and Nuclear Signaling
€139 - €419
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:ETV6 Rabbit Polyclonal Antibody
SKU:CAB15668
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human ETV6 (NP_001978.1).
Sequence:MSET PAQC SIKQ ERIS YTPP ESPV PSYA SSTP LHVP VPRA LRME EDSI RLPA HLRL QPIY WSRD DVAQ WLKW AENE FSLR PIDS NTFE MNGK ALLL LTKE DFRY RSPH SGDV LYEL LQHI LKQR KPRI LFSP FFHP GNSI HTQP EVIL HQNH EEDN CVQR TPRP SVDN VHHN PPTI ELLH RSRS PITT NHRP SPDP EQRP LRSP LDNM IRRL SPAE RAQG PRPH QENN HQES YPLS VSPM ENNH CPAS SESH PKPS SPRQ ESTR VIQL MPSP IMHP LILN PRHS VDFK QSRL SEDG LHRE
Tested Applications:WB ELISA
Recommended Dilution:WB,1:500 - 1:2000
Synonyms:TEL; THC5; TEL/ABL; ETV6
Positive Sample:HepG2,Mouse lung,Mouse spleen,Rat testis
Conjugate:Unconjugated
Cellular Localization:Nucleus.
Calculated MW:53kDa
Observed MW:55kDa

This gene encodes an ETS family transcription factor. The product of this gene contains two functional domains: a N-terminal pointed (PNT) domain that is involved in protein-protein interactions with itself and other proteins, and a C-terminal DNA-binding domain. Gene knockout studies in mice suggest that it is required for hematopoiesis and maintenance of the developing vascular network. This gene is known to be involved in a large number of chromosomal rearrangements associated with leukemia and congenital fibrosarcoma.

Purification Method:Affinity purification
Gene ID:2120
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using ETV6 Rabbit pAb (CAB15668) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.

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