The ETV5 Polyclonal Antibody (CAB17927) is specifically designed for research involving ETV5, a transcription factor known for its role in regulating gene expression and cell differentiation. This antibody, produced in rabbits, is highly specific for human samples and has been validated for use in Western blotting applications. By binding to the ETV5 protein, this antibody enables researchers to detect and analyze ETV5 expression in various cell types.ETV5 is a crucial regulator of cell proliferation, differentiation, and survival, making it a key player in a wide range of biological processes. Studies have shown that dysregulation of ETV5 expression is associated with various diseases, including cancer, developmental disorders, and neurological conditions.
Understanding the function of ETV5 is essential for uncovering its role in disease pathology and identifying potential therapeutic targets.Overall, the ETV5 Polyclonal Antibody offers researchers a valuable tool for investigating the biological functions of ETV5 and its potential implications in disease development. Its high specificity and reliability in Western blot applications make it an ideal choice for studies in molecular biology, oncology, and developmental biology.
Product Name:
ETV5 Rabbit Polyclonal Antibody
SKU:
CAB17927
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-510 of human ETV5 (P41161).
Enables DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in cellular response to oxidative stress; negative regulation of transcription by RNA polymerase II; and positive regulation of transcription by RNA polymerase II. Located in nucleoplasm.
Purification Method:
Affinity purification
Gene ID:
2119
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from A-431 cells, using ETV5 Rabbit pAb (CAB17927) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
