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ETV4 Transcription Factor Activity Assay

SKU:
TFAB00099
Product Type:
ELISA Kit
ELISA Type:
Transcription Factor Assay
Analytes:
ETV4
Reactivity:
Human
€599
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Description

system_update_altDatasheet

ETV4 Transcription Factor Activity Assay

The ETV4 Transcription Factor Activity Assay offered by Assay Genie is a reliable and sensitive kit designed for the detection of ETV4 transcription factor activity in various samples. This assay provides accurate and reproducible results, making it suitable for a wide range of research applications in the field of transcription regulation.ETV4, also known as PEER-1, is a key transcription factor involved in cancer development and progression. It plays a critical role in regulating gene expression patterns that control cell growth, migration, and invasion.

By measuring ETV4 activity, researchers can gain valuable insights into the molecular mechanisms underlying cancer and potentially identify new therapeutic targets.The Assay Genie ETV4 Transcription Factor Activity Assay is easy to use and can be applied to a variety of sample types, making it a versatile tool for studying ETV4-mediated transcriptional regulation. With its high sensitivity and specificity, this kit is essential for researchers looking to unravel the complex role of ETV4 in cancer biology.

Product Name:ETV4 Transcription Factor Activity Assay
Product Code:TFAB00099
Target:ETV4
Synonyms:Adenovirus E1A enhancer-binding protein, E1A-F, Polyomavirus enhancer activator 3 homolog, Protein PEA3
Reactivity:Human
Sample Types:Nuclear or cell lysates

The Assay Genie ETV4 transcription factor activity assay allows for the detection and qualitative analysis of endogenous levels of activated transcription factors in a variety of nuclear and cell lysates

Assay Genie ELISA kits are designed to significantly reduce experiment time and ensure sensitivity and flexibility for high-throughput screening.

Assay Time:4.5 hours
Detection Method:Colorimetric 450 nm
Size:12 x 8-Well Microstrips
Storage:4°C for 6 months
UniProt Protein Function:ETV4: Transcriptional activator that binds to the enhancer of the adenovirus E1A gene; the core-binding sequence is 5'[AC]GGA[AT]GT-3'. Belongs to the ETS family.
UniProt Protein Details:

Protein type:DNA-binding

Chromosomal Location of Human Ortholog: 17q21

Cellular Component: nucleolus

Molecular Function:protein binding

Biological Process: transcription from RNA polymerase II promoter; regulation of transcription from RNA polymerase II promoter; positive regulation of transcription from RNA polymerase II promoter; motor axon guidance; stem cell differentiation; cell differentiation; negative regulation of mammary gland epithelial cell proliferation

UniProt Code:P43268
NCBI GenInfo Identifier:62512145
NCBI Gene ID:2118
NCBI Accession:P43268.3
UniProt Secondary Accession:P43268,Q96AW9, A8K314, B7Z5J3, B7Z9J6,
UniProt Related Accession:P43268
Molecular Weight:484
NCBI Full Name:ETS translocation variant 4
NCBI Synonym Full Names:ets variant 4
NCBI Official Symbol:ETV4  
NCBI Official Synonym Symbols:E1AF; PEA3; E1A-F; PEAS3  
NCBI Protein Information:ETS translocation variant 4; adenovirus E1A enhancer-binding protein; polyomavirus enhancer activator 3 homolog; EWS protein/E1A enhancer binding protein chimera; ets variant gene 4 (E1A enhancer-binding protein, E1AF)
UniProt Protein Name:ETS translocation variant 4
UniProt Synonym Protein Names:Adenovirus E1A enhancer-binding protein; E1A-F; Polyomavirus enhancer activator 3 homolog; Protein PEA3
Protein Family:ETS translocation
UniProt Gene Name:ETV4  
UniProt Entry Name:ETV4_HUMAN
AntibodiesELISA Kits
Anti-ETV4 Antibody (CAB13860)Human ETV4 (ETS translocation variant 4) ELISA Kit (HUFI04380)
Anti-ETV4 Antibody (CAB15667)
Anti-Pea3 / ETV4 Antibody (CAB5797)
ETV4 Antibody (PACO03645)
ETV4 Antibody (PACO09156)

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