The ETV4 Polyclonal Antibody (CAB5797) is a valuable tool for researchers studying the ETV4 protein, a transcription factor involved in regulating gene expression and cell growth. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blotting applications. By binding to the ETV4 protein, this antibody allows for the detection and analysis of ETV4 in various cell types, making it a versatile tool for investigations in molecular biology and cancer research.ETV4, also known as E1A-F, is a member of the ETS family of transcription factors and plays a crucial role in the regulation of cell proliferation, differentiation, and tumorigenesis.
Its involvement in cancer progression and metastasis highlights the importance of studying ETV4 in the context of oncology research. By understanding the mechanisms by which ETV4 influences cellular processes, researchers can uncover potential therapeutic targets for the treatment of cancer and other diseases characterized by abnormal cell growth.
Product Name:
Pea3/ETV4 Rabbit Polyclonal Antibody
SKU:
CAB5797
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant Protein corresponding to a sequence within amino acids 1-284 of human ETV4 (NP_001977.1).
Enables DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in positive regulation of keratinocyte differentiation and positive regulation of transcription by RNA polymerase II. Located in chromosome and nucleolus.
Purification Method:
Affinity purification
Gene ID:
2118
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of various lysates using Pea3 / ETV4 Rabbit pAb (CAB5797) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
