The ETV4 Polyclonal Antibody (CAB13860) is a valuable tool for researchers studying the ETV4 protein, a transcription factor that plays a crucial role in various cellular processes, including cell proliferation, differentiation, and tumorigenesis. This antibody, generated in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications.ETV4, also known as E1AF, is a member of the ETS family of transcription factors and is known to regulate the expression of genes involved in development and cancer progression. Its overexpression has been associated with numerous cancers, making it a promising target for research into cancer biology and potential therapeutic interventions.
By utilizing the ETV4 Polyclonal Antibody, researchers can effectively detect and analyze ETV4 protein expression in different cell types, providing valuable insights into its role in cellular processes and disease pathology. This antibody is a valuable tool for studies in oncology, molecular biology, and gene regulation, offering the opportunity to advance our understanding of ETV4 function and its implications in various disease states.
Product Name:
ETV4 Rabbit Polyclonal Antibody
SKU:
CAB13860
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 79-178 of human ETV4 (NP_001977.1).
Enables DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in positive regulation of keratinocyte differentiation and positive regulation of transcription by RNA polymerase II. Located in chromosome and nucleolus.
Purification Method:
Affinity purification
Gene ID:
2118
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from Mouse heart, using ETV4 Rabbit pAb (CAB13860) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
