The ETV4 Monoclonal Antibody is a crucial tool for researchers studying ETV4, a transcription factor known for its role in various cellular processes including cell proliferation, differentiation, and tumorigenesis. This antibody, generated through hybridoma technology, specifically targets ETV4, allowing for accurate detection and analysis in a variety of experimental settings.ETV4, also known as E1AF, is a key player in promoting cell growth and migration, making it a potential target for cancer therapy. Its overexpression has been linked to various cancers, highlighting the importance of studying its regulation and function.
The ETV4 Monoclonal Antibody offers researchers a reliable tool for investigating the role of ETV4 in cancer progression and potential therapeutic strategies.Validated for use in techniques such as immunohistochemistry and immunofluorescence, this antibody provides researchers with the ability to visualize and measure ETV4 expression in tissue samples, aiding in the understanding of its involvement in disease development. By targeting ETV4 with precision and sensitivity, this monoclonal antibody is a valuable asset for advancing research in oncology and molecular biology.
Product Name:
ETV4 Monoclonal Antibody
SKU:
CAB23126
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
A synthesized peptide derived from human ETV4.
Tested Applications:
WBELISA
Recommended Dilution:
WB,1:2000 - 1:9000
Synonyms:
E1AF; PEA3; E1A-F; PEAS3; ETV4
Positive Sample:
K-562
Conjugate:
Unconjugated
Cellular Localization:
Nucleus.
Calculated MW:
54kDa
Observed MW:
61kDa
Enables DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in positive regulation of keratinocyte differentiation and positive regulation of transcription by RNA polymerase II. Located in chromosome and nucleolus.
Purification Method:
Affinity purification
Gene ID:
2118
Clone Number:
ARC58618
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates, using ETV4 antibody (CAB23126) at 1:8000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 120s.
