The ETS2 Polyclonal Antibody (CAB16845) is a valuable tool for research involving the ETS2 transcription factor, which plays a key role in the regulation of gene expression related to cell proliferation, differentiation, and transformation. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By binding to the ETS2 protein, this antibody enables researchers to study its function and activity in various cell types, making it an essential tool for studies in cancer research and developmental biology.ETS2 is a member of the ETS family of transcription factors and is known to be involved in a wide range of cellular processes, including cell growth, apoptosis, and differentiation.
Dysregulation of ETS2 expression has been linked to various diseases, such as cancer, developmental disorders, and autoimmune diseases. Understanding the role of ETS2 in these pathological conditions is essential for the development of targeted therapies and diagnostic tools.Overall, the ETS2 Polyclonal Antibody (CAB16845) offers researchers a reliable and specific tool for studying the function of the ETS2 transcription factor in different biological contexts, contributing to the advancement of knowledge in the fields of cancer biology, developmental biology, and molecular genetics.
Product Name:
ETS2 Rabbit Polyclonal Antibody
SKU:
CAB16845
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 300-400 of human ETS2 (NP_005230.1).
This gene encodes a transcription factor which regulates genes involved in development and apoptosis. The encoded protein is also a protooncogene and shown to be involved in regulation of telomerase. A pseudogene of this gene is located on the X chromosome. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
2114
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using ETS2 Rabbit pAb (CAB16845) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3min.
