The ETS1 Rabbit Polyclonal Antibody (CAB1596) is a valuable tool for researchers studying the ETS1 transcription factor, involved in regulating gene expression and cell development. This antibody, raised in rabbits, has high reactivity with human samples and is validated for use in various applications, including Western blotting. By binding specifically to the ETS1 protein, researchers can detect and analyze its presence in a wide range of cell types, making it a versatile tool for studies in molecular biology and cancer research.
ETS1 is a key player in controlling gene expression involved in cell proliferation, differentiation, and apoptosis. It has been implicated in various diseases, including cancer, autoimmune disorders, and inflammatory conditions. Understanding the role of ETS1 in these disease processes is essential for developing targeted therapies and treatments. The ETS1 Rabbit Polyclonal Antibody (CAB1596) provides researchers with a reliable and specific tool for investigating the function of ETS1 in both normal and diseased cells.
Product Name:
ETS1 Polyclonal Antibody
SKU:
CAB1596
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human ETS1 (NP_005229.1).
This gene encodes a member of the ETS family of transcription factors, which are defined by the presence of a conserved ETS DNA-binding domain that recognizes the core consensus DNA sequence GGAA/T in target genes. These proteins function either as transcriptional activators or repressors of numerous genes, and are involved in stem cell development, cell senescence and death, and tumorigenesis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Purification Method:
Affinity purification
Gene ID:
2113
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of lysates from Mouse kidney, using ETS1 Rabbit pAb (CAB1596) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
