The ETS1 Rabbit Monoclonal Antibody (CAB19603) is a valuable tool for researchers studying the ETS1 transcription factor, a key regulator of gene expression involved in various cellular processes, including cell proliferation, differentiation, and apoptosis. This antibody, generated in rabbits, exhibits high specificity and sensitivity for human samples, making it ideal for use in immunohistochemistry, immunofluorescence, and Western blot applications.ETS1 is known to play a crucial role in the development and function of the immune system, as well as in the progression of cancer.
By targeting the ETS1 protein, researchers can further investigate its function and potential as a therapeutic target in diseases such as leukemia, lymphoma, and inflammatory disorders. The use of the ETS1 Rabbit Monoclonal Antibody allows for precise detection and analysis of ETS1 expression in various cell types, providing valuable insights into its role in both normal and pathological conditions.
Product Name:
ETS1 Rabbit Monoclonal Antibody
SKU:
CAB19603
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human ETS1 (P14921).
This gene encodes a member of the ETS family of transcription factors, which are defined by the presence of a conserved ETS DNA-binding domain that recognizes the core consensus DNA sequence GGAA/T in target genes. These proteins function either as transcriptional activators or repressors of numerous genes, and are involved in stem cell development, cell senescence and death, and tumorigenesis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Purification Method:
Affinity purification
Gene ID:
2113
Clone Number:
ARC0082
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using ETS1 antibody (CAB19603) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1min.
