The ETS1 Polyclonal Antibody (CAB15666) is a valuable tool for researchers studying the ETS1 protein, a transcription factor involved in the regulation of gene expression. This antibody, generated in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By binding to the ETS1 protein, this antibody enables precise detection and analysis in a variety of cell types, making it an essential component for studies in molecular biology and cancer research.ETS1 is a key regulator of cellular processes such as proliferation, differentiation, and apoptosis, making it a promising target for understanding disease mechanisms and developing potential therapeutic interventions.
Dysregulation of ETS1 has been implicated in various diseases, including cancer, autoimmune disorders, and inflammatory conditions, highlighting the importance of studying its function in different contexts. By using the ETS1 Polyclonal Antibody, researchers can gain valuable insights into the role of ETS1 in disease progression and potentially uncover new targets for treatment strategies.
Product Name:
ETS1 Rabbit Polyclonal Antibody
SKU:
CAB15666
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 342-441 of human ETS1 (NP_005229.1).
This gene encodes a member of the ETS family of transcription factors, which are defined by the presence of a conserved ETS DNA-binding domain that recognizes the core consensus DNA sequence GGAA/T in target genes. These proteins function either as transcriptional activators or repressors of numerous genes, and are involved in stem cell development, cell senescence and death, and tumorigenesis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Purification Method:
Affinity purification
Gene ID:
2113
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from Jurkat cells, using ETS1 Rabbit pAb (CAB15666) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
