The ETFDH Polyclonal Antibody (CAB6585) is a powerful tool for researchers studying the ETFDH protein, which is involved in the electron transport chain and fatty acid metabolism. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By binding to the ETFDH protein, this antibody allows for accurate detection and analysis in a variety of cell types.ETFDH is essential for the breakdown of fatty acids and plays a crucial role in energy production within the cell. Mutations in the ETFDH gene have been linked to disorders such as riboflavin-responsive multiple acyl-CoA dehydrogenase deficiency (RR-MADD), a rare metabolic disorder that affects the body's ability to break down fats and proteins.
Understanding the function of ETFDH is important for research into metabolic diseases and potential therapeutic interventions.Overall, the ETFDH Polyclonal Antibody (CAB6585) is a valuable tool for researchers investigating the role of ETFDH in metabolism and related diseases. Its specificity and reliability make it an essential component for studies in biochemistry, molecular biology, and metabolic research.
Product Name:
ETFDH Rabbit Polyclonal Antibody
SKU:
CAB6585
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 318-617 of human ETFDH (NP_004444.2).
This gene encodes a component of the electron-transfer system in mitochondria and is essential for electron transfer from a number of mitochondrial flavin-containing dehydrogenases to the main respiratory chain. Mutations in this gene are associated with glutaric acidemia. Alternatively spliced transcript variants that encode distinct isoforms have been observed.
Purification Method:
Affinity purification
Gene ID:
2110
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using ETFDH Rabbit pAb (CAB6585) at 1:3000 dilution.Secondary antibody:HRP Goat Anti-Rabbit IgG (H+L)(CABS014) at 1:10000 dilution.Lysates / proteins: 25 μg per lane.Blocking buffer: 3 % nonfat dry milk in TBST.Detection:ECL Basic Kit (AbGn00020).Exposuretime: 15s.
