The ETFB Polyclonal Antibody (CAB16043) is a versatile tool for researchers studying the ETFB protein, which plays a key role in the electron transfer flavoprotein pathway in the mitochondria. This antibody, produced in rabbits, shows high reactivity with human samples and is validated for use in Western blot applications. By specifically binding to the ETFB protein, researchers can easily detect and analyze its expression in various cell types.The ETFB protein is essential for the oxidation of fatty acids and amino acids in the mitochondria, making it crucial for energy metabolism.
Dysregulation of the ETFB pathway has been linked to various metabolic disorders and diseases, making it a promising target for research in the fields of metabolism, nutrition, and mitochondrial function.By using the ETFB Polyclonal Antibody, researchers can gain valuable insights into the role of the ETFB protein in cellular metabolism and its implications for human health. This antibody is a valuable tool for those studying metabolic disorders, as well as those exploring potential therapeutic targets for conditions related to mitochondrial dysfunction.
Product Name:
ETFB Rabbit Polyclonal Antibody
SKU:
CAB16043
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 80-230 of human ETFB (NP_001976.1).
This gene encodes electron-transfer-flavoprotein, beta polypeptide, which shuttles electrons between primary flavoprotein dehydrogenases involved in mitochondrial fatty acid and amino acid catabolism and the membrane-bound electron transfer flavoprotein ubiquinone oxidoreductase. The gene deficiencies have been implicated in type II glutaricaciduria. Alternatively spliced transcript variants have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
2109
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using ETFB Rabbit pAb (CAB16043) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
