ETFA Rabbit Polyclonal Antibody (CAB7670)
- SKU:
- CAB7670
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | ETFA Rabbit Polyclonal Antibody |
SKU: | CAB7670 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-333 of human ETFA (NP_000117.1). |
Sequence: | MFRA AAPG QLRR AASL LRFQ STLV IAEH ANDS LAPI TLNT ITAA TRLG GEVS CLVA GTKC DKVA QDLC KVAG IAKV LVAQ HDVY KGLL PEEL TPLI LATQ KQFN YTHI CAGA SAFG KNLL PRVA AKLE VAPI SDII AIKS PDTF VRTI YAGN ALCT VKCD EKVK VFSV RGTS FDAA ATSG GSAS SEKA SSTS PVEI SEWL DQKL TKSD RPEL TGAK VVVS GGRG LKSG ENFK LLYD LADQ LHAA VGAS RAAV DAGF VPND MQVG QTGK IVAP ELYI AVGI SGAI QHLA GMKD SKTI VAIN KDPE APIF QVAD YGIV ADLF KVVP EMTE ILKK K |
Tested Applications: | WB IHC-P IP ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 IP,0.5μg-4μg antibody for 200μg-400μg extracts of whole cells |
Synonyms: | EMA; GA2; MADD; ETFA |
Positive Sample: | Mouse heart,Rat heart,Mouse liver,Rat liver |
Conjugate: | Unconjugated |
Cellular Localization: | Mitochondrion matrix. |
Calculated MW: | 35kDa |
Observed MW: | 35kDa |
ETFA participates in catalyzing the initial step of the mitochondrial fatty acid beta-oxidation. It shuttles electrons between primary flavoprotein dehydrogenases and the membrane-bound electron transfer flavoprotein ubiquinone oxidoreductase. Defects in electron-transfer-flavoprotein have been implicated in type II glutaricaciduria in which multiple acyl-CoA dehydrogenase deficiencies result in large excretion of glutaric, lactic, ethylmalonic, butyric, isobutyric, 2-methyl-butyric, and isovaleric acids. Two transcript variants encoding different isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 2108 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |