The Estrogen-Related Receptor Alpha Rabbit Monoclonal Antibody (CAB4176) is a valuable tool for researchers studying the role of ERRα in various biological processes. ERRα is a transcription factor that plays a crucial role in regulating energy metabolism, cell proliferation, and differentiation. This antibody, raised in rabbits, exhibits high specificity and sensitivity for detecting ERRα in human samples.Validated for use in applications such as Western blot and immunohistochemistry, this antibody enables precise detection and analysis of ERRα in a variety of cell types and tissue samples.
Its ability to specifically bind to ERRα protein makes it an ideal choice for studies in areas such as metabolism, aging, and cancer research.The importance of ERRα in metabolic regulation and its association with various diseases make it a compelling target for further investigation. By using this antibody to study ERRα expression and activity, researchers can gain valuable insights into the molecular mechanisms underlying these processes, potentially leading to the development of novel therapeutic strategies for metabolic disorders and cancer.
Product Name:
ESRRA Rabbit Monoclonal Antibody
SKU:
CAB4176
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human ESRRA (P11474).
The protein encoded by this gene is a nuclear receptor that is most closely related to the estrogen receptor. This protein acts as a site-specific transcription factor and interacts with members of the PGC-1 family of transcription cofactors to regulate the expression of most genes involved in cellular energy production as well as in the process of mitochondrial biogenesis. A processed pseudogene of ESRRA is located on chromosome 13q12.1.
Purification Method:
Affinity purification
Gene ID:
2101
Clone Number:
ARC0919
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using ESRRA Rabbit mAb (CAB4176) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 3min.
