The ESRRAPolyclonal Antibody (CAB1798) is a valuable tool for researchers studying the estrogen-related receptor alpha (ESRRA), a transcription factor known for its role in regulating energy metabolism and mitochondrial function. This antibody, generated in rabbits, displays high specificity and sensitivity towards human samples and has been validated for use in various applications, including Western blotting.ESRRA is a key regulator of genes involved in oxidative metabolism and plays a crucial role in the maintenance of cellular energy balance. Dysregulation of ESRRA has been linked to a variety of metabolic disorders, making it an attractive target for further investigation in research areas such as metabolic diseases, cancer, and aging.
By utilizing the ESRRAPolyclonal Antibody (CAB1798), researchers can effectively study the expression and function of ESRRA in different cell types and tissues, allowing for a deeper understanding of its biological roles and potential therapeutic implications. Whether investigating metabolic pathways or exploring the impact of ESRRA dysregulation in disease states, this antibody is a valuable tool for advancing scientific knowledge in the field of molecular biology and biochemistry.
Product Name:
ESRRA Rabbit Polyclonal Antibody
SKU:
CAB1798
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-76 of human ESRRA (NP_004442.3).
The protein encoded by this gene is a nuclear receptor that is most closely related to the estrogen receptor. This protein acts as a site-specific transcription factor and interacts with members of the PGC-1 family of transcription cofactors to regulate the expression of most genes involved in cellular energy production as well as in the process of mitochondrial biogenesis. A processed pseudogene of ESRRA is located on chromosome 13q12.1.
Purification Method:
Affinity purification
Gene ID:
2101
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using ESRRA antibody (CAB1798) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.
