The ESrrA Polyclonal Antibody (CAB14184) is a valuable tool for researchers studying ESrrA, a transcription factor involved in various cellular processes including metabolism and development. This antibody, produced in rabbits, is highly specific for detection of ESrrA in human samples and is validated for use in applications such as immunohistochemistry and immunofluorescence.ESrrA, also known as estrogen-related receptor alpha, plays a key role in mediating estrogen signaling and is implicated in diseases like breast cancer and metabolic disorders.
Understanding the function of ESrrA is essential for unraveling its role in these pathologies and developing targeted therapies. The ESrrA Polyclonal Antibody enables researchers to accurately detect and study ESrrA expression and localization in different cell types and tissues, providing valuable insights into its biological functions.
Product Name:
ESRRA Rabbit Polyclonal Antibody
SKU:
CAB14184
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-76 of human ESRRA (NP_004442.3).
The protein encoded by this gene is a nuclear receptor that is most closely related to the estrogen receptor. This protein acts as a site-specific transcription factor and interacts with members of the PGC-1 family of transcription cofactors to regulate the expression of most genes involved in cellular energy production as well as in the process of mitochondrial biogenesis. A processed pseudogene of ESRRA is located on chromosome 13q12.1.
Purification Method:
Affinity purification
Gene ID:
2101
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using ESRRA Rabbit pAb (CAB14184) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
