The ESRP1 Polyclonal Antibody (CAB14626) is specifically designed for research involving ESRP1, a key RNA-binding protein involved in the regulation of alternative splicing. This antibody, raised in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding to the ESRP1 protein, this antibody enables the accurate detection and analysis of ESRP1 expression in various cell types, making it an essential tool for studies in molecular biology and cancer research.
ESRP1 plays a crucial role in the regulation of alternative splicing events, influencing the diversity of mRNA isoforms produced in cells. Dysregulation of ESRP1 expression has been implicated in various diseases, including cancer and neurodegenerative disorders. Understanding the function of ESRP1 is essential for unraveling its role in health and disease and may lead to the development of novel therapeutic strategies targeting alternative splicing processes.
Product Name:
ESRP1 Rabbit Polyclonal Antibody
SKU:
CAB14626
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human ESRP1 (NP_060167.2).
ESPR1 is an epithelial cell-type-specific splicing regulator (Warzecha et al., 2009 [PubMed 19285943]).
Purification Method:
Affinity purification
Gene ID:
54845
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using ESRP1 Rabbit pAb (CAB14626) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
