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ESR1 Monoclonal Antibody [LSERASC1] (CPAB0580)

SKU:
CPAB0580
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Universal
Host Species:
Mouse
Isotype:
IgG
Clone:
LSERASC1
Applications:
WB
IHC
FC
$792
Frequently bought together:

Description

system_update_alt Datasheet

ESR1 Monoclonal Antibody [LSERASC1] (CPAB0580)

The ESR1 Monoclonal Antibody (CPAB0580) is a vital tool for researchers studying estrogen receptor 1 (ESR1) in various cellular contexts. This antibody, produced in rabbits, is highly specific and reacts strongly with human samples, making it ideal for Western blot applications. By binding to the ESR1 protein, this antibody allows for the detection and analysis of ESR1 expression in different cell types.ESR1, also known as estrogen receptor alpha, plays a crucial role in mediating the effects of estrogen in various physiological processes, including development, reproduction, and metabolism. Dysregulation of ESR1 has been linked to several diseases, including breast cancer and osteoporosis, making it a key target for therapeutic intervention.

Studying the activity of ESR1 with this antibody can provide valuable insights into the mechanisms underlying these diseases and may lead to the development of novel treatment strategies.Overall, the ESR1 Monoclonal Antibody (CPAB0580) is a reliable tool for researchers interested in understanding the role of ESR1 in health and disease. Its high specificity and sensitivity make it a valuable asset for studies in the fields of endocrinology, cancer biology, and hormone signaling pathways.

Product Name:ESR1 Antibody
Product Sku:CPAB0580
Size:500μg
Host Species:Mouse
Immunogen:Recombinant human ER-alpha.
Clone:LSERASC1.
Reactivity:Other bodies
Applications:Western Blot, Immunohistochemistry, Flow Cytometry
Purification Method:Protein A
Isotype:IgG
Background:Estrogen receptors ? (ER?, ER; NR3A1) is a member of the steroid hormone receptor family.  ER? is a ligand-activated transcription factor.  ER? contain DNA binding and ligand binding domains.   ER? is expressed in a wide variety of tissues, including ovary, uterus, breast, prostate, testis, epididymis, bones, bladder, kidney, heart, vessel wall, pituitary gland and hypothalamus. ER plays a variety of important roles in the maintenance of the reproductive, cardiovascular, musculoskeletal and central nervous systems.   The natural ligand for ER is 17?-estradiol, the classical estrogenic compound.  The binding of estrogen to ER induces a conformational change and triggers a cascade of events, including dissociation from heat shock proteins, receptor dimerization, phosphorylation and the association of the hormone activated receptor with specific regulatory elements in target genes.
Synonyms:ER-alpha
Storage Buffer:Lyophilized: store at 4°C. After reconstitution, if not intended for use within a month, aliquot and store at -20°C.

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