ESPN Rabbit Polyclonal Antibody (CAB15908)
- SKU:
- CAB15908
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | ESPN Rabbit Polyclonal Antibody |
SKU: | CAB15908 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 585-854 of human ESPN (NP_113663.2). |
Sequence: | CAAD PKAS RELP PPPP PPPP PLPE AASS PPPA PPLP LESA GPGC GQRR SSSS TGST KSFN MMSP TGDN SELL AEIK AGKS LKPT PQSK GLTT VFSG IGQP AFQP DSPL PSVS PALS PVRS PTPP AAGF QPLL NGSL VPVP PTTP APGV QLDV EALI PTHD EQGR PIPE WKRQ VMVR KMQL KMQE EEEQ RRKE EEEE ARLA SMPA WRRD LLRK KLEE EREQ KRKE EERQ KQEE LRRE KEQS EKLR TLGY DESK LAPW QRQV ILKK GDIA KY |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 |
Synonyms: | USH1M; DFNB36; LP2654; ESPN |
Positive Sample: | Mouse testis,Rat testis |
Conjugate: | Unconjugated |
Cellular Localization: | Cell projection, Cytoplasm, cytoskeleton, microvillus, stereocilium. |
Calculated MW: | 92kDa |
Observed MW: | 110-120kDa |
This gene encodes a multifunctional actin-bundling protein. It plays a major role in regulating the organization, dimensions, dynamics, and signaling capacities of the actin filament-rich, microvillus-type specializations that mediate sensory transduction in various mechanosensory and chemosensory cells. Mutations in this gene are associated with autosomal recessive neurosensory deafness, and autosomal dominant sensorineural deafness without vestibular involvement.
Purification Method: | Affinity purification |
Gene ID: | 83715 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |