The ESPN Polyclonal Antibody (CAB15908) is a valuable tool for researchers studying ESPN, a protein involved in immune regulation and immune response modulation. This antibody, raised in rabbits, is highly specific for human samples and has been validated for Western blot applications. By binding to the ESPN protein, it allows for the detection and analysis of ESPN in various cell types, making it ideal for studies in immunology and cancer research.ESPN, also known as an immune inhibitory receptor, plays a critical role in immune homeostasis by regulating inflammation and inhibiting allergic reactions.
Its importance in immune response modulation makes it a promising target for research into diseases such as cancer, autoimmune disorders, and chronic inflammatory conditions. Understanding the function of ESPN is essential for the development of therapies that manipulate immune function in these disease contexts.Overall, the ESPN Polyclonal Antibody (CAB15908) provides researchers with a reliable tool for studying ESPN and its role in immune regulation, inflammation, and disease, ultimately contributing to advancements in immunology and cancer research.
Product Name:
ESPN Rabbit Polyclonal Antibody
SKU:
CAB15908
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 585-854 of human ESPN (NP_113663.2).
This gene encodes a multifunctional actin-bundling protein. It plays a major role in regulating the organization, dimensions, dynamics, and signaling capacities of the actin filament-rich, microvillus-type specializations that mediate sensory transduction in various mechanosensory and chemosensory cells. Mutations in this gene are associated with autosomal recessive neurosensory deafness, and autosomal dominant sensorineural deafness without vestibular involvement.
Purification Method:
Affinity purification
Gene ID:
83715
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using ESPN Rabbit pAb (CAB15908) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
