The ESE1 Rabbit Monoclonal Antibody (CAB5236) is a vital tool for researchers studying ESE1, a transcription factor known for its role in regulating gene expression and cell proliferation. This antibody, generated from rabbit cells, exhibits high specificity and sensitivity when detecting ESE1 in human samples, making it perfect for Western blot applications.ESE1, also known as epithelium-specific ETS transcription factor-1, is involved in various biological processes, including cell differentiation, apoptosis, and cancer development.
Its aberrant expression has been linked to tumorigenesis, making it a promising target for cancer research and drug development.By using the ESE1 Rabbit Monoclonal Antibody, researchers can effectively study the function and regulation of ESE1 in different cell types, providing valuable insights into its role in oncogenesis and potential therapeutic interventions. This antibody is a valuable tool for scientists interested in unraveling the complexity of ESE1 signaling pathways and its implications in cancer biology.
Product Name:
ESE1/ELF3 Rabbit Monoclonal Antibody
SKU:
CAB5236
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-371 of human ESE1/ELF3 (P78545).
WB,1:500 - 1:2000 ChIP,5μg antibody for 10μg-15μg of ChromatinCUT&Tag, 10⁵ cells /1 μg
Synonyms:
ERT; ESX; EPR-1; ESE-1; ESE1/ELF3
Positive Sample:
A549,A-431,Mouse lung,Rat kidney
Conjugate:
Unconjugated
Cellular Localization:
Cytoplasm, Nucleus.
Calculated MW:
41kDa
Observed MW:
42kDa
Enables DNA-binding transcription activator activity, RNA polymerase II-specific and sequence-specific double-stranded DNA binding activity. Involved in inflammatory response; negative regulation of transcription, DNA-templated; and positive regulation of transcription by RNA polymerase II. Located in Golgi apparatus; cytosol; and nucleoplasm.
Purification Method:
Affinity purification
Gene ID:
1999
Clone Number:
ARC1191
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
CUT&Tag was performed using the CUT&Tag Assay Kit (pAG-Tn5) for Illumina(RK20265) from 10⁵ HepG5 with 1μg ESE1 (CAB5236) , along with a Goat Anti-Rabbit IgG(H+L). The CUT&Tag results indicate the enrichment pattern of ESE1 in representative gene loci (MARK4), as shown in figure.
