The ESD Polyclonal Antibody (CAB6228) is a vital tool for researchers studying ESD, a protein involved in epithelial cell differentiation and tissue homeostasis. This antibody, produced in rabbits, exhibits high specificity and sensitivity when used with human samples in various applications, with particular validation for immunohistochemistry techniques. By binding to ESD, it enables precise detection and analysis of this protein in different cell types, making it an essential resource for investigations in the fields of cell biology and cancer research.ESD, or Epithelial Stromal Interaction 1, plays a crucial role in maintaining the integrity and function of epithelial tissues by regulating cell proliferation and differentiation.
Its involvement in tissue repair and regeneration processes makes it a promising target for research on diseases affecting epithelial structures, such as cancer and inflammatory disorders. Unraveling the functions of ESD is key to unlocking potential therapeutic strategies that target epithelial cell behaviors and functions, with implications for improving clinical outcomes in various pathological conditions.
Product Name:
ESD Rabbit Polyclonal Antibody
SKU:
CAB6228
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-282 of human ESD (NP_001975.1).
This gene encodes a serine hydrolase that belongs to the esterase D family. The encoded enzyme is active toward numerous substrates including O-acetylated sialic acids, and it may be involved in the recycling of sialic acids. This gene is used as a genetic marker for retinoblastoma and Wilson's disease.
Purification Method:
Affinity purification
Gene ID:
2098
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using ESD Rabbit pAb (CAB6228) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
