The ERP57 Rabbit Monoclonal Antibody (CAB4376) is a powerful tool for researchers studying the protein ERP57, an important molecule involved in protein folding and quality control in the endoplasmic reticulum. This antibody, developed using rabbit monoclonal technology, is highly specific and sensitive for detecting ERP57 in a variety of samples.Ideal for use in Western blotting and immunohistochemistry applications, the ERP57 Rabbit Monoclonal Antibody (CAB4376) enables precise and reliable detection and analysis of ERP57 in different cell types and tissues.
Its high reactivity with human samples makes it a valuable asset for studies in protein folding, quality control mechanisms, and ER stress response pathways.By targeting ERP57, researchers can gain insights into its role in cellular function and disease processes, including cancer, neurodegenerative disorders, and metabolic diseases. Understanding the functions of ERP57 can pave the way for developing new therapeutic strategies targeting protein folding and ER stress, with potential implications for a wide range of human health conditions.
Product Name:
ERp57 Rabbit Monoclonal Antibody
SKU:
CAB4376
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 100-200 of human ERp57 (P30101).
This gene encodes a protein of the endoplasmic reticulum that interacts with lectin chaperones calreticulin and calnexin to modulate folding of newly synthesized glycoproteins. The protein was once thought to be a phospholipase; however, it has been demonstrated that the protein actually has protein disulfide isomerase activity. It is thought that complexes of lectins and this protein mediate protein folding by promoting formation of disulfide bonds in their glycoprotein substrates. This protein also functions as a molecular chaperone that prevents the formation of protein aggregates.
Purification Method:
Affinity purification
Gene ID:
2923
Clone Number:
ARC0987
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using ERp57 Rabbit mAb (CAB4376) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
