ERp57 Rabbit Monoclonal Antibody (CAB4376)
- SKU:
- CAB4376
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- ER60
- ERp57
- ERp60
- ERp61
- GRP57
- GRP58
- HEL-S-269
- HEL-S-93n
- HsT17083
- P58
- PI-PLC
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | ERp57 Rabbit Monoclonal Antibody |
SKU: | CAB4376 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 100-200 of human ERp57 (P30101). |
Sequence: | YPTL KIFR DGEE AGAY DGPR TADG IVSH LKKQ AGPA SVPL RTEE EFKK FISD KDAS IVGF FDDS FSEA HSEF LKAA SNLR DNYR FAHT NVES LVNE YDDN G |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 |
Synonyms: | P58; ER60; ERp57; ERp60; ERp61; GRP57; GRP58; PI-PLC; HsT17083; HEL-S-269; HEL-S-93n |
Positive Sample: | 293T,Hep G2 |
Conjugate: | Unconjugated |
Cellular Localization: | Endoplasmic reticulum, Endoplasmic reticulum lumen, Melanosome. |
Calculated MW: | 54kDa |
Observed MW: | 57kDa |
This gene encodes a protein of the endoplasmic reticulum that interacts with lectin chaperones calreticulin and calnexin to modulate folding of newly synthesized glycoproteins. The protein was once thought to be a phospholipase; however, it has been demonstrated that the protein actually has protein disulfide isomerase activity. It is thought that complexes of lectins and this protein mediate protein folding by promoting formation of disulfide bonds in their glycoprotein substrates. This protein also functions as a molecular chaperone that prevents the formation of protein aggregates.
Purification Method: | Affinity purification |
Gene ID: | 2923 |
Clone Number: | ARC0987 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |