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Erlin-2 Rabbit Monoclonal Antibody (CAB0781)

SKU:
CAB0781
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Synonyms:
ERLIN2
C8orf2
NET32
SPFH2
SPG18
Research Area:
Metabolism
$167 - $503
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:Erlin-2 Rabbit Monoclonal Antibody
SKU:CAB0781
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 50-150 of human Erlin-2 (O94905).
Sequence:HLML PFIT SYKS VQTT LQTD EVKN VPCG TSGG VMIY FDRI EVVN FLVP NAVY DIVK NYTA DYDK ALIF NKIH HELN QFCS VHTL QEVY IELF DQID ENLK L
Tested Applications:WB IHC-P ELISA
Recommended Dilution:WB,1:500 - 1:1000 IHC-P,1:50 - 1:200
Synonyms:NET32; SPFH2; SPG18; C8orf2; Erlin-2
Positive Sample:293T,PC-3,OVCAR3,C2C12
Conjugate:Unconjugated
Cellular Localization:Endoplasmic reticulum membrane, Single-pass type II membrane protein.
Calculated MW:38kDa
Observed MW:43kDa

This gene encodes a member of the SPFH domain-containing family of lipid raft-associated proteins. The encoded protein is localized to lipid rafts of the endoplasmic reticulum and plays a critical role in inositol 1,4,5-trisphosphate (IP3) signaling by mediating ER-associated degradation of activated IP3 receptors. Mutations in this gene are a cause of spastic paraplegia-18 (SPG18). Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Purification Method:Affinity purification
Gene ID:11160
Clone Number:ARC2538
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using Erlin-2 Rabbit mAb (CAB0781) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.

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