ERLIN1 Rabbit Polyclonal Antibody (CAB14843)
- SKU:
- CAB14843
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Frequently bought together:
Description
Product Name: | ERLIN1 Rabbit Polyclonal Antibody |
SKU: | CAB14843 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 259-348 of human ERLIN1 (NP_006450.2). |
Sequence: | KADA EYYA AHKY ATSN KHKL TPEY LELK KYQA IASN SKIY FGSN IPNM FVDS SCAL KYSD IRTG RESS LPSK EALE PSGE NVIQ NKES TG |
Tested Applications: | WB IHC-P IP ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 IP,0.5μg-4μg antibody for 200μg-400μg extracts of whole cells |
Synonyms: | KE04; KEO4; SPFH1; SPG62; Erlin-1; C10orf69; ERLIN1 |
Positive Sample: | 293T,HepG2,BxPC-3,DU145,OVCAR3,Mouse kidney,Rat testis |
Conjugate: | Unconjugated |
Cellular Localization: | Endoplasmic reticulum membrane, Single-pass type II membrane protein. |
Calculated MW: | 39kDa |
Observed MW: | 39kDa |
The protein encoded by this gene is part of a protein complex that mediates degradation of inositol 1,4,5-trisphosphate receptors in the endoplasmic reticulum. The encoded protein also binds cholesterol and regulates the SREBP signaling pathway, which promotes cellular cholesterol homeostasis. Defects in this gene have been associated with spastic paraplegia 62.
Purification Method: | Affinity purification |
Gene ID: | 10613 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |