ERK5 Rabbit Monoclonal Antibody (CAB3948)
- SKU:
- CAB3948
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Cycle
Description
Product Name: | ERK5 Rabbit Monoclonal Antibody |
SKU: | CAB3948 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 717-816 of human ERK5 (Q13164). |
Sequence: | LSKS QVED PLPP VFSG TPKG SGAG YGVG FDLE EFLN QSFD MGVA DGPQ DGQA DSAS LSAS LLAD WLEG HGMN PADI ESLQ REIQ MDSP MLLA DLPD LQDP |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | BMK1; ERK4; ERK5; PRKM7 |
Positive Sample: | Mouse lung,Mouse brain,Rat brain,HeLa,293T |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Nucleus, PML body. |
Calculated MW: | 88kDa |
Observed MW: | 115kDa |
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is specifically activated by mitogen-activated protein kinase kinase 5 (MAP2K5/MEK5). It is involved in the downstream signaling processes of various receptor molecules including receptor type kinases, and G protein-coupled receptors. In response to extracelluar signals, this kinase translocates to cell nucleus, where it regulates gene expression by phosphorylating, and activating different transcription factors. Four alternatively spliced transcript variants of this gene encoding two distinct isoforms have been reported.
Purification Method: | Affinity purification |
Gene ID: | 5598 |
Clone Number: | ARC0871 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |