The ERK1 Rabbit Monoclonal Antibody (CAB19561) is a high-quality antibody designed for research involving the extracellular signal-regulated kinase 1 (ERK1) protein. ERK1 is a key regulator of cellular proliferation, differentiation, and survival, making it a crucial target for studies in cell signaling and cancer research.This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. It specifically binds to the ERK1 protein, enabling precise detection and analysis in various cell types. This makes it an ideal tool for researchers interested in understanding the role of ERK1 in normal cellular processes and disease pathways.
ERK1 dysregulation has been implicated in various diseases, including cancer, neurodegenerative disorders, and cardiovascular diseases. By studying ERK1 protein expression and activity using this antibody, researchers can gain valuable insights into the molecular mechanisms underlying these conditions and potentially develop targeted therapies. The ERK1 Rabbit Monoclonal Antibody is a valuable tool for advancing research in cell signaling, cancer biology, and therapeutic development.
Product Name:
ERK1 Rabbit Monoclonal Antibody
SKU:
CAB19561
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human ERK1 (P27361).
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act in a signaling cascade that regulates various cellular processes such as proliferation, differentiation, and cell cycle progression in response to a variety of extracellular signals. This kinase is activated by upstream kinases, resulting in its translocation to the nucleus where it phosphorylates nuclear targets. Alternatively spliced transcript variants encoding different protein isoforms have been described.
Purification Method:
Affinity purification
Gene ID:
5595
Clone Number:
ARC2591
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates, using [KD Validated] ERK1 Rabbit mAb (CAB19561) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
