The ERK1 Monoclonal Antibody (CAB21975) offered by Assay Genie is an essential tool for researchers studying the ERK1 protein, a key player in cellular signaling pathways. This antibody, produced using a monoclonal antibody technology, is specifically designed for use in Western blot applications and is highly reactive with human samples.ERK1, also known as Extracellular Signal-Regulated Kinase 1, is involved in regulating various cellular processes such as cell growth, differentiation, and survival. Dysregulation of ERK1 signaling has been implicated in diseases such as cancer, making it a crucial target for therapeutic interventions.
By using the ERK1 Monoclonal Antibody, researchers can effectively detect and analyze ERK1 protein levels in different cell types, enabling a better understanding of its role in disease development. This antibody is a valuable tool for studies in cancer research, drug discovery, and signal transduction pathways. Overall, the ERK1 Monoclonal Antibody from Assay Genie is a reliable and high-quality reagent that can advance research in the field of cellular signaling and disease mechanisms.
Product Name:
ERK1 Monoclonal Antibody
SKU:
CAB21975
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 200-300 of human ERK1ERK1/2 (P27361/P28482).
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act in a signaling cascade that regulates various cellular processes such as proliferation, differentiation, and cell cycle progression in response to a variety of extracellular signals. This kinase is activated by upstream kinases, resulting in its translocation to the nucleus where it phosphorylates nuclear targets. Alternatively spliced transcript variants encoding different protein isoforms have been described.
Purification Method:
Affinity purification
Gene ID:
5595
Clone Number:
ARC51164
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of lysates from Rat brain, using ERK1 Rabbit mAb (CAB21975) at1:27000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
