The ERGIC2 Polyclonal Antibody (CAB7369) is a vital tool for researchers studying ERGIC2, a protein essential for protein trafficking and secretion processes within the cell. This antibody, generated in rabbits, exhibits high specificity and sensitivity towards human samples, making it an excellent choice for Western blot applications. By binding to the ERGIC2 protein, this antibody enables the detection and analysis of ERGIC2 in various cell types, facilitating investigations in cell biology and molecular biology.ERGIC2 plays a crucial role in the early secretory pathway, specifically in the transport of newly synthesized proteins from the endoplasmic reticulum to the Golgi apparatus. Dysregulation of ERGIC2 function has been linked to various human diseases, highlighting its importance in cellular homeostasis.
Research into ERGIC2 is particularly relevant in understanding mechanisms underlying protein trafficking and secretion defects, providing insights into pathologies such as neurodegenerative disorders and metabolic syndromes.By utilizing the ERGIC2 Polyclonal Antibody (CAB7369), researchers can delve deeper into the intricate processes involving ERGIC2, paving the way for novel discoveries and potential therapeutic interventions targeting ERGIC2-associated diseases. Its versatility and reliability make it an indispensable tool for advancing scientific knowledge in cell biology and related fields.
Product Name:
ERGIC2 Rabbit Polyclonal Antibody
SKU:
CAB7369
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 55-310 of human ERGIC2 (NP_057654.2).
ERGIC2, or PTX1, is a ubiquitously expressed nuclear protein that is downregulated in prostate carcinoma (Kwok et al., 2001 [PubMed 11445006]).
Purification Method:
Affinity purification
Gene ID:
51290
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using ERGIC2 antibody (CAB7369) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
