The ERGIC1 Polyclonal Antibody (PACO09134) is a valuable tool for researchers studying ERGIC1, a protein involved in vesicle trafficking and protein transport within the cell. This antibody, produced in rabbits, exhibits high reactivity with ERGIC1 in human samples and is validated for use in Western blot applications. By binding specifically to ERGIC1, this antibody enables the detection and analysis of ERGIC1 protein levels in various cell types, making it an essential tool for studies in cell biology and molecular biology.ERGIC1, also known as Endoplasmic Reticulum-Golgi Intermediate Compartment 1, plays a key role in the sorting and transportation of proteins from the endoplasmic reticulum to the Golgi apparatus.
Understanding the function and regulation of ERGIC1 is crucial for unraveling the mechanisms of intracellular trafficking and protein processing, with implications for various cellular processes and diseases. The ERGIC1 Polyclonal Antibody provides researchers with a reliable means to investigate the role of ERGIC1 in cellular pathways and disease states, advancing our knowledge of cell biology and potential therapeutic targets.
ERGIC1: Possible role in transport between endoplasmic reticulum and Golgi. Belongs to the ERGIC family. 3 isoforms of the human protein are produced by alternative splicing.Protein type: Membrane protein, integral; Membrane protein, multi-passChromosomal Location of Human Ortholog: 5q35.1Cellular Component: Golgi membrane; endoplasmic reticulum membrane; ER-Golgi intermediate compartment membrane; membrane; ER-Golgi intermediate compartment; integral to membraneMolecular Function: protein bindingBiological Process: ER to Golgi vesicle-mediated transport
UniProt Protein Details:
NCBI Summary:
This gene encodes a cycling membrane protein which is an endoplasmic reticulum-golgi intermediate compartment (ERGIC) protein which interacts with other members of this protein family to increase their turnover. [provided by RefSeq, Jul 2008]