ERF Antibody (PACO21790)
- SKU:
- PACO21790
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
ERF Antibody (PACO21790)
The ERF Polyclonal Antibody (PAC021790) is a valuable tool for researchers studying the ETS domain-containing transcription factor ERF. This antibody, generated in rabbits, is highly specific to human samples and is well-suited for use in Western blot applications. By targeting the ERF protein, this antibody allows for the detection and analysis of ERF expression in various cell types, making it an ideal choice for studies in molecular biology and cancer research.ERF, a transcription factor involved in the regulation of gene expression, plays a critical role in cellular processes such as growth, differentiation, and apoptosis.
Dysregulation of ERF has been implicated in a variety of diseases, including cancer, making it an attractive target for further investigation. Understanding the role of ERF in these disease processes can provide valuable insights for the development of targeted therapies and diagnostics.Overall, the ERF Polyclonal Antibody (PAC021790) offers researchers a reliable tool for exploring the functions of ERF in health and disease. Its high specificity and sensitivity make it a valuable asset for advancing our understanding of the molecular mechanisms underlying various pathological conditions.
| Antibody Name: | ERF Antibody (PACO21790) |
| Antibody SKU: | PACO21790 |
| Size: | 100ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:50-1:100 |
| Species Reactivity: | Human, Mouse |
| Immunogen: | Synthesized peptide derived from internal of human ERF. |
| Form: | Liquid |
| Storage Buffer: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen Olsen J.V., Cell 127:635-648(2006). |
| Clonality: | Polyclonal |
| Conjugate: | Non-conjugated |
 | Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using ERF antibody. |
| Synonyms: | ETS-domain transcription factor ERF; Ets2 repressor factor; |
| UniProt Protein Function: | ERF: potent transcriptional repressor that binds to the H1 element of the ETS2 promoter. Belongs to the ETS family of transcription factors. Its function is regulated by phosphorylation. |
| UniProt Protein Details: | Protein type:DNA-binding; Transcription factor Chromosomal Location of Human Ortholog: 19q13 Cellular Component: cytosol; Golgi apparatus; nucleoplasm; nucleus Molecular Function:sequence-specific DNA binding; transcription corepressor activity Biological Process: cell cycle; cell differentiation; negative regulation of transcription from RNA polymerase II promoter; transcription, DNA-dependent Disease: Craniosynostosis 4 |
| NCBI Summary: | ETS2 is a transcription factor and protooncogene involved in development, apoptosis, and the regulation of telomerase. The protein encoded by this gene binds to the ETS2 promoter and is a strong repressor of ETS2 transcription. Several transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Aug 2015] |
| UniProt Code: | P50548 |
| NCBI GenInfo Identifier: | 50403684 |
| NCBI Gene ID: | 2077 |
| NCBI Accession: | P50548.2 |
| UniProt Secondary Accession: | P50548,Q59G38, Q9UPI7, B2RAP1, B7Z4R0, |
| UniProt Related Accession: | P50548 |
| Molecular Weight: | 49,965 Da |
| NCBI Full Name: | ETS domain-containing transcription factor ERF |
| NCBI Synonym Full Names: | ETS2 repressor factor |
| NCBI Official Symbol: | ERFÂ Â |
| NCBI Official Synonym Symbols: | PE2; CRS4; PE-2Â Â |
| NCBI Protein Information: | ETS domain-containing transcription factor ERF |
| UniProt Protein Name: | ETS domain-containing transcription factor ERF |
| UniProt Synonym Protein Names: | Ets2 repressor factor; PE-2 |
| Protein Family: | Essential recombination function protein |
| UniProt Gene Name: | ERFÂ Â |
| UniProt Entry Name: | ERF_HUMAN |
| Antibodies | ELISA Kits |
| Phospho-ERF (T526) Antibody (PACO03638) | ERF Transcription Factor Activity Assay |
| ERF Antibody (PACO03639) | |
| ERF Antibody (PACO06474) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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